The role of Nrf2 in the attenuation of cardiovascular disease.

نویسندگان

  • Danielle J Reuland
  • Joe M McCord
  • Karyn L Hamilton
چکیده

Oxidative stress is a component of many human diseases, including cardiovascular diseases (CVD). Exercise and various phytochemicals activate nuclear factor (erythroid-derived 2)-like 2 (Nrf2), the master regulator of antioxidant defenses, and attenuate CVD. This review highlights Nrf2 regulation by exercise and phytochemicals and the role of Nrf2 as a therapeutic target in CVD.

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عنوان ژورنال:
  • Exercise and sport sciences reviews

دوره 41 3  شماره 

صفحات  -

تاریخ انتشار 2013